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Mapping of RNA polymerase on mammalian genes in cells and nuclei.

The assembly of an RNA polymerase II initiation complex at a promoter is associated with the melting of the DNA template to allow the polymerase to read the DNA sequence and synthesize the corresponding RNA. Using the specific single-stranded modifying reagent KMnO4 and a new genomic sequencing tech...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mirkovitch, J, Darnell, J E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1992
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC275673/
https://ncbi.nlm.nih.gov/pubmed/1384813
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