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IL-17 Receptor Signaling Negatively Regulates C/EBPβ by Sequential Phosphorylation of the Regulatory 2 Domain‡

IL-17, hallmark cytokine of the newly-described “Th17” population, signals through a novel subclass of receptors, yet surprisingly little is known about mechanisms of IL-17 receptor signaling. IL-17 activates target gene expression via NF-κB and two members of the C/EBP transcription factor family,...

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Bibliographic Details
Main Authors: Shen, Fang, Li, Nan, Gade, Padmaja, Kalvakolanu, Dhananjaya V., Weibley, Timothy, Doble, Brad, Woodgett, James R., Wood, Troy D., Gaffen, Sarah L.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2754870/
https://ncbi.nlm.nih.gov/pubmed/19244213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000066
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