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Is Cdc25 a Druggable Target?

Proper control of cell cycle progression requires the functionality of a small family of activating phosphatases termed Cdc25, which have been implicated in cancer and Alzheimer's disease. These protein tyrosine phosphatases are therefore recognized as attractive molecular targets for small mol...

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Bibliographic Details
Main Authors: Lazo, John S., Wipf, Peter
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752834/
https://ncbi.nlm.nih.gov/pubmed/19075566
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