Hippocampal Atrophy and Apolipoprotein E Genotype are Independently Associated with Alzheimer's Disease

A variety of anatomic and functional neuroimaging findings are associated with Alzheimer's Disease (AD). One of the strongest imaging associations identified is between AD and hippocampal atrophy. The ∈4 allele of the apolipoprotein E (APOE) gene increases the risk of developing AD and lowers t...

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Bibliographic Details
Main Authors: Jack, Clifford R., Petersen, Ronald C., Xu, Yue Cheng, O'Brien, Peter C., Tangalos, Eric G., Smith, Glenn E., Ivnik, Robert J., Kokmen, Emre
Format: Artigo
Language:Inglês
Published: 1998
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752747/
https://ncbi.nlm.nih.gov/pubmed/9506546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.410430307
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