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Induction of Human T cell Tolerance to Pig Xenoantigens via Thymus Transplantation in Mice with an Established Human Immune System

Thymus xenotransplantation has been shown to induce tolerance to porcine xenografts in mice and to permit survival of α1,3Gal-transferase knockout porcine kidney xenografts for months in non-human primates. We evaluated the ability of porcine thymus xenotransplantation to induce human T cell toleran...

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Bibliographic Details
Main Authors: Habiro, Katsuyoshi, Sykes, Megan, Yang, Yong-Guang
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752337/
https://ncbi.nlm.nih.gov/pubmed/19459808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2009.02646.x
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