FACT and the Proteasome Promote Promoter Chromatin Disassembly and Transcriptional Initiation

The packaging of the eukaryotic genome into chromatin represses gene expression by blocking access of the general transcription machinery to the underlying DNA sequences. Accordingly, eukaryotes have developed a variety of mechanisms to disrupt, alter, or disassemble nucleosomes from promoter region...

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Main Authors: Ransom, Monica, Williams, Stephanie K., Dechassa, Mekonnen L., Das, Chandrima, Linger, Jeffrey, Adkins, Melissa, Liu, Chengwei, Bartholomew, Blaine, Tyler, Jessica K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2009
Teme:
Transcription, Chromatin, and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749120/
https://ncbi.nlm.nih.gov/pubmed/19574230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.019562
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