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An age-dependent association of mannose-binding lectin-2 genetic variants on HIV-1-related disease in children

BACKGROUND: Mannose-binding lectin (MBL) is part of the lectin pathway of complement activation against various pathogens; however, its role in innate immune responses against HIV-1 infection in children is unknown. OBJECTIVE: This study evaluated the effects of mannose-binding lectin-2 (MBL2) allel...

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Bibliographic Details
Main Authors: Singh, Kumud K., Lieser, Alexis, Ruan, Ping K., Fenton, Terry, Spector, Stephen A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748310/
https://ncbi.nlm.nih.gov/pubmed/18602571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.05.025
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