Fibrils connect microtubule tips with kinetochores suggesting ways to couple tubulin dynamics to chromosome motion

Kinetochores of mitotic chromosomes are coupled to spindle microtubules in ways that allow the energy from tubulin dynamics to drive chromosome motion. Most kinetochore-associated microtubule ends display curving “protofilaments,” strands of tubulin dimers that bend away from the microtubule axis. B...

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Bibliografiske detaljer
Main Authors: McIntosh, J.R., Grishchuk, E.L., Morphew, M., Efremov, A.K., Zhudenkov, K., Volkov, V.A., Cheeseman, I.M., Desai, A., Mastronarde, D.N., Ataullakhanov, F.I.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746696/
https://ncbi.nlm.nih.gov/pubmed/18957206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.08.038
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