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A-type nuclear lamins act as transcriptional repressors when targeted to promoters

Regions of heterochromatin are often found at the periphery of the mammalian nucleus, juxtaposed to the nuclear lamina. Genes in these regions are likely maintained in a transcriptionally silent state, although other locations at the nuclear periphery associated with nuclear pores are sites of activ...

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Main Authors: Lee, Damian C., Welton, K. Linnea, Smith, Erica D., Kennedy, Brian K.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2746445/
https://ncbi.nlm.nih.gov/pubmed/19272320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.01.003
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