INHIBITION OF NITRIC OXIDE SYNTHASE BY COBALAMINS AND COBINAMIDES*

Cobalamins (Cbl) are important co-factors for methionine synthase and methylmalonyl-coA mutase. Certain corrins also bind nitric oxide (NO), quenching its bioactivity. To determine if corrins would inhibit NO synthase (NOS), we measured their effects on 14-C-L-arginine-to-14-C-L-citrulline conversio...

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Bibliografiske detaljer
Main Authors: Weinberg, J. Brice, Chen, Youwei, Jiang, Ning, Beasley, Bethany E., Salerno, John C., Ghosh, Dipak K.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745708/
https://ncbi.nlm.nih.gov/pubmed/19328848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.03.017
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