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An iterative strategy combining biophysical criteria and duration hidden Markov models for structural predictions of Chlamydia trachomatis σ(66 )promoters

BACKGROUND: Promoter identification is a first step in the quest to explain gene regulation in bacteria. It has been demonstrated that the initiation of bacterial transcription depends upon the stability and topology of DNA in the promoter region as well as the binding affinity between the RNA polym...

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Hlavní autoři: Mallios, Ronna R, Ojcius, David M, Ardell, David H
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2743672/
https://ncbi.nlm.nih.gov/pubmed/19715597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-271
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