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Requirement of Cell Cycle and Apoptosis Regulator 1 for Target Gene Activation by Wnt and β-Catenin and for Anchorage-independent Growth of Human Colon Carcinoma Cells

Aberrant Wnt signaling promotes oncogenesis by increasing cellular levels of β-catenin, which associates with DNA-bound transcription factors and activates Wnt target genes. However, the molecular mechanism by which β-catenin mediates gene expression is still poorly understood. Here, we show that ce...

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Sonraí Bibleagrafaíochta
Main Authors: Ou, Chen-Yin, Kim, Jeong Hoon, Yang, Catherine K., Stallcup, Michael R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742827/
https://ncbi.nlm.nih.gov/pubmed/19520846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.014332
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