Neuroprotective effects of a nanocrystal formulation of sPLA(2) inhibitor PX-18 in cerebral ischemia/reperfusion in gerbils

The group IIA secretory phospholipase A2 (sPLA(2)-IIA) has been studied extensively because of its involvement in inflammatory processes. Up-regulation of this enzyme has been shown in a number of neurodegenerative diseases including cerebral ischemia and Alzheimer’s disease. PX-18 is a selective sP...

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Detalhes bibliográficos
Main Authors: Wang, Qun, Sun, Albert Y., Pardeike, Jana, Müller, Rainer H., Simonyi, Agnes, Sun, Grace Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742555/
https://ncbi.nlm.nih.gov/pubmed/19527696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2009.06.022
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