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NMR Structure of the amino-terminal domain of the lambda integrase protein in complex with DNA: immobilization of a flexible tail facilitates beta-sheet recognition of the major groove

The integrase protein (Int) from bacteriophage lambda is the archetype member of the tyrosine recombinase family, a large group of enzymes that rearrange DNA in all domains of life. Int catalyzes the insertion and excision of the viral genome into and out of the E. coli chromosome. Recombination tra...

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Bibliografiske detaljer
Main Authors: Fadeev, Evgeny A., Sam, My D., Clubb, Robert T.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739574/
https://ncbi.nlm.nih.gov/pubmed/19324050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.041
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