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Resistance to Antiestrogen Arzoxifene Is Mediated by Overexpression of Cyclin D1

Resistance to tamoxifen treatment occurs in approximately 50% of the estrogen receptor (ER)α-positive breast cancer patients. Resistant patients would benefit from treatment with other available antiestrogens. Arzoxifene is an effective growth inhibitor of ERα-positive breast cancer cells, including...

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Detalhes bibliográficos
Main Authors: Zwart, Wilbert, Rondaij, Mariska, Jalink, Kees, Sharp, Z. Dave, Mancini, Michael A., Neefjes, Jacques, Michalides, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737554/
https://ncbi.nlm.nih.gov/pubmed/19477949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0268
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