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Ovarian Cancer Cell Detachment and Multicellular Aggregate Formation Are Regulated by MT1-MMP: A Potential Role in Intra-Peritoneal Metastatic Dissemination

An early event in the metastasis of epithelial ovarian carcinoma is shedding of cells from the primary tumor into the peritoneal cavity, followed by diffuse intra-peritoneal (i.p.) seeding of secondary lesions. Anchorage-independent metastatic cells are present as both single cells and multi-cellula...

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Detalhes bibliográficos
Main Authors: Moss, Natalie M., Barbolina, Maria V., Liu, Yueying, Sun, Limin, Munshi, Hidayatullah G., Stack, M. Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737080/
https://ncbi.nlm.nih.gov/pubmed/19706774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4151
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