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Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7
Paraplegin is an m-AAA protease of the mitochondrial inner membrane that is linked to hereditary spastic paraplegias. The gene encodes an FtsH-homology protease domain in tandem with an AAA+ homology ATPase domain. The protein is believed to form a hexamer that uses ATPase-driven conformational chan...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2734466/ https://ncbi.nlm.nih.gov/pubmed/19841671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006975 |
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