Crystal Structure of the ATPase Domain of the Human AAA+ Protein Paraplegin/SPG7

Paraplegin is an m-AAA protease of the mitochondrial inner membrane that is linked to hereditary spastic paraplegias. The gene encodes an FtsH-homology protease domain in tandem with an AAA+ homology ATPase domain. The protein is believed to form a hexamer that uses ATPase-driven conformational chan...

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Bibliografiske detaljer
Main Authors: Karlberg, Tobias, van den Berg, Susanne, Hammarström, Martin, Sagemark, Johanna, Johansson, Ida, Holmberg-Schiavone, Lovisa, Schüler, Herwig
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2734466/
https://ncbi.nlm.nih.gov/pubmed/19841671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006975
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