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Leptin Indirectly Regulates Gonadotropin-Releasing Hormone Neuronal Function

The adipose-derived hormone leptin communicates information about metabolic status to the hypothalamic GnRH neuronal system. It is unclear whether leptin can act directly on GnRH neurons. To examine this, we used three approaches. First, the presence of leptin-induced signal transducer and activator...

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Bibliografiske detaljer
Main Authors: Quennell, Janette H., Mulligan, Alicia C., Tups, Alexander, Liu, Xinhuai, Phipps, Sarah J., Kemp, Christopher J., Herbison, Allan E., Grattan, David R., Anderson, Greg M.
Format: Artigo
Sprog:Inglês
Udgivet: The Endocrine Society 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732287/
https://ncbi.nlm.nih.gov/pubmed/19179437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1693
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