Leptin Indirectly Regulates Gonadotropin-Releasing Hormone Neuronal Function

The adipose-derived hormone leptin communicates information about metabolic status to the hypothalamic GnRH neuronal system. It is unclear whether leptin can act directly on GnRH neurons. To examine this, we used three approaches. First, the presence of leptin-induced signal transducer and activator...

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Main Authors: Quennell, Janette H., Mulligan, Alicia C., Tups, Alexander, Liu, Xinhuai, Phipps, Sarah J., Kemp, Christopher J., Herbison, Allan E., Grattan, David R., Anderson, Greg M.
Format: Artigo
Jezik:Inglês
Izdano: The Endocrine Society 2009
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2732287/
https://ncbi.nlm.nih.gov/pubmed/19179437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1693
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