The chemokine Bv8/prokineticin 2 is up-regulated in inflammatory granulocytes and modulates inflammatory pain

Neutrophil migration into injured tissues is invariably accompanied by pain. Bv8/prokineticin 2 (PK2), a chemokine characterized by a unique structural motif comprising five disulfide bonds, is highly expressed in inflamed tissues associated to infiltrating cells. Here, we demonstrate the fundamenta...

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Main Authors: Giannini, Elisa, Lattanzi, Roberta, Nicotra, Annalisa, Campese, Antonio F., Grazioli, Paola, Screpanti, Isabella, Balboni, Gianfranco, Salvadori, Severo, Sacerdote, Paola, Negri, Lucia
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731841/
https://ncbi.nlm.nih.gov/pubmed/19667192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903720106
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