Use of Biological Therapy to Enhance Both Virotherapy and Adoptive T-Cell Therapy for Cancer

To protect viral particles from neutralization, sequestration, nonspecific adhesion, and mislocalization following systemic delivery, we have previously exploited the natural tumor-homing properties of antigen-specific CD8+ T cells. Thus, OT-I T cells, preloaded in vitro with the oncolytic vesicular...

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Autors principals: Kottke, Timothy, Diaz, Rosa M, Kaluza, Karen, Pulido, Jose, Galivo, Feorillo, Wongthida, Phonphimon, Thompson, Jill, Willmon, Candice, Barber, Glen N, Chester, John, Selby, Peter, Strome, Scott, Harrington, Kevin, Melcher, Alan, Vile, Richard G
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729459/
https://ncbi.nlm.nih.gov/pubmed/18827807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.212
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