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Interferon β induces mature dendritic cell apoptosis through caspase-11/caspase-3 activation

Although interferon β (IFNβ) decreases relapse rate and disease activity in multiple sclerosis (MS), the mechanisms involved have not been elucidated. The present study is the first report on the apoptotic effect of IFNβ in mature, but not immature, myeloid dendritic cells (DCs). Both exogenous IFNβ...

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Detalhes bibliográficos
Main Authors: Yen, Jui-Hung, Ganea, Doina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727412/
https://ncbi.nlm.nih.gov/pubmed/19531658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-196592
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