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Histone H3 N-terminus regulates higher order structure of yeast heterochromatin

In budding yeast, telomeres and the mating type (HM) loci are found in a heterochromatin-like silent structure initiated by Rap1 and extended by the interaction of Silencing Information Regulator (Sir) proteins with histones. Binding data demonstrate that both the H3 and H4 N-terminal domains requir...

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Autores principales: Sperling, Adam S., Grunstein, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2726386/
https://ncbi.nlm.nih.gov/pubmed/19666585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906866106
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