Low Frequency Variants in the Exons Only Encoding Isoform A of HNF1A Do Not Contribute to Susceptibility to Type 2 Diabetes

BACKGROUND: There is considerable interest in the hypothesis that low frequency, intermediate penetrance variants contribute to the proportion of Type 2 Diabetes (T2D) susceptibility not attributable to the common variants uncovered through genome-wide association approaches. Genes previously implic...

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Main Authors: Jafar-Mohammadi, Bahram, Groves, Christopher J., Owen, Katharine R., Frayling, Timothy M., Hattersley, Andrew T., McCarthy, Mark I., Gloyn, Anna L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720540/
https://ncbi.nlm.nih.gov/pubmed/19672314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006615
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