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Elucidating the Significance of β-Hydride Elimination and the Dynamic Role of Acid/Base Chemistry in a Palladium-Catalyzed Aerobic Oxidation of Alcohols

The mechanistic details of aerobic alcohol oxidation with catalytic Pd(IiPr)(OAc)(2)(H(2)O) (IiPr = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene) are disclosed. Under optimal conditions, β-hydride elimination is rate-limiting supported by kinetic studies including a high primary kinetic isotope...

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Detaylı Bibliyografya
Asıl Yazarlar: Mueller, Jaime A., Goller, Christopher P., Sigman, Matthew S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2720309/
https://ncbi.nlm.nih.gov/pubmed/15291576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja047794s
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