Autoimmune pancreatitis results from loss of TGFβ signalling in S100A4-positive dendritic cells

BACKGROUND AND AIMS: Autoimmune pancreatitis (AIP) is a poorly understood human disease affecting the exocrine pancreas. The goal of the present study was to elucidate the pathogenic mechanisms underlying pancreatic autoimmunity in a murine disease model. METHODS: A transgenic mouse with an S100A4/f...

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Autors principals: Boomershine, C S, Chamberlain, A, Kendall, P, Afshar-Sharif, A-R, Huang, H, Washington, M K, Lawson, W E, Thomas, J W, Blackwell, T S, Bhowmick, N A
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2009
Matèries:
Pancreas
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719085/
https://ncbi.nlm.nih.gov/pubmed/19625278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2008.170779
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