Development of an Artificial-Antigen-Presenting-Cell-Based Assay for the Detection of Low-Frequency Virus-Specific CD8(+) T Cells in Whole Blood, with Application for Measles Virus

Evaluation of the immune responses induced by childhood vaccines requires measurement of T-cell, as well as antibody, responses. However, cellular immune responses are often not analyzed because of technical hurdles and the volume of blood required. Therefore, a sensitive and specific assay for anti...

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Bibliographic Details
Main Authors: Ndhlovu, Zaza M., Angenendt, Monika, Heckel, Diana, Schneck, Jonathan P., Griffin, Diane E., Oelke, Mathias
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Microbial Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2708410/
https://ncbi.nlm.nih.gov/pubmed/19494085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00365-08
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