Progressive thalamocortical neuron loss in Cln5 deficient mice: distinct effects in Finnish variant late infantile NCL

Finnish variant LINCL (vLINCL(Fin)) is the result of mutations in the CLN5 gene. To gain insights into the pathological staging of this fatal pediatric disorder, we have undertaken a stereological analysis of the CNS of Cln5 deficient mice (Cln5(-/-)) at different stages of disease progression. Cons...

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Main Authors: von Schantz, Carina, Kielar, Catherine, Hansen, Stine N, Pontikis, Charlie C, Alexander, Noreen A, Kopra, Outi, Jalanko, Anu, Cooper, Jonathan D
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704904/
https://ncbi.nlm.nih.gov/pubmed/19385065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2009.02.001
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