Crystal Structure of the C-Terminal Cytoplasmic Domain of Non-Structural Protein 4 from Mouse Hepatitis Virus A59

BACKGROUND: The replication of coronaviruses takes place on cytoplasmic double membrane vesicles (DMVs) originating in the endoplasmic reticulum (ER). Three trans-membrane non-structural proteins, nsp3, nsp4 and nsp6, are understood to be membrane anchors of the coronavirus replication complex. Nsp4...

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Autori principali: Xu, Xiaoling, Lou, Zhiyong, Ma, Yanlin, Chen, Xuehui, Yang, Zhangsheng, Tong, Xiaohang, Zhao, Qi, Xu, Yuanyuan, Deng, Hongyu, Bartlam, Mark, Rao, Zihe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703826/
https://ncbi.nlm.nih.gov/pubmed/19593433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006217
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