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Myelin Basic Protein-Reactive T Cells Persist in an Inactive State in the Bone Marrow of Lewis Rats that have Recovered from Autoimmune Encephalomyelitis

Lewis rats immunized with guinea pig myelin basic protein residues 68-86 develop acute experimental autoimmune encephalomyelitis and recover. The predominant T cell receptor expressed by the encephalitogenic T cells is TCRBV8S2. They persist in bone marrow many weeks after recovery. CD3 is down-regu...

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Main Authors: Kheradmand, Taba, Wolf, Norbert A., Swanborg, Robert H.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699580/
https://ncbi.nlm.nih.gov/pubmed/19211156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2009.01.018
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