Natural Triterpenic Diols Promote Apoptosis in Astrocytoma Cells through ROS-Mediated Mitochondrial Depolarization and JNK Activation

BACKGROUND: Triterpene alcohols and acids are multifunctional compounds widely distributed throughout the plant kingdom that exhibit a variety of beneficial health properties, being synthetic analogs of oleanolic acid under clinical evaluation as anti-tumoral therapeutic agents. However, the antineo...

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Bibliografske podrobnosti
Main Authors: Martín, Rubén, Ibeas, Elvira, Carvalho-Tavares, Juliana, Hernández, Marita, Ruiz-Gutierrez, Valentina, Nieto, María Luisa
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2009
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2695006/
https://ncbi.nlm.nih.gov/pubmed/19543395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005975
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