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Efficient siRNA Delivery into Primary Cells by Peptide Transduction-dsRNA Binding Domain (PTD-DRBD) Fusion Protein
Short interfering RNA (siRNA) induced RNA interference (RNAi) responses allow for discovery research and performing large scale screening1-5; however, due to their size and anionic charge, siRNAs have no bioavailability to enter cells4,5. Current approaches fail to deliver siRNAs into a high percent...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694965/ https://ncbi.nlm.nih.gov/pubmed/19448630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.1541 |
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