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Temozolomide and cisplatin in relapsed/refractory acute leukemia
Cisplatin depletes MGMT and increases the sensitivity of leukemia cells to temozolomide. We performed a phase I study of cisplatin and temozolomide in patients with relapsed and refractory acute leukemia. Fifteen patients had AML, 3 had ALL, and 2 had biphenotypic leukemia. The median number of prio...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694825/ https://ncbi.nlm.nih.gov/pubmed/19463179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8722-2-21 |
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