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Regulatory T cell differentiation of thymocytes does not require a dedicated antigen-presenting cell but is under T cell-intrinsic developmental control

The majority of regulatory T cells (T(regs)) are believed to be of thymic origin. It has been hypothesized that this may result from unique intrathymic environmental cues, possibly requiring a dedicated antigen-presenting cell (APC). However, T cell-intrinsic developmental regulation of the suscepti...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wirnsberger, Gerald, Mair, Florian, Klein, Ludger
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694684/
https://ncbi.nlm.nih.gov/pubmed/19515822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901877106
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