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Precise Gene-Dose Alleles for Chemical Genetics
Modulating gene dose is an effective way to alter protein levels and modify phenotypes to understand gene function. In addition, combining gene-dose alleles with chemical perturbation can provide insight into drug–gene interactions. Here, we present a strategy that combines diverse loss-of-function...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
Genetics Society of America
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691769/ https://ncbi.nlm.nih.gov/pubmed/19332878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.103036 |
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