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Precise Gene-Dose Alleles for Chemical Genetics

Modulating gene dose is an effective way to alter protein levels and modify phenotypes to understand gene function. In addition, combining gene-dose alleles with chemical perturbation can provide insight into drug–gene interactions. Here, we present a strategy that combines diverse loss-of-function...

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Bibliografische gegevens
Hoofdauteurs: Yan, Zhun, Berbenetz, Nicolas M., Giaever, Guri, Nislow, Corey
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Genetics Society of America 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2691769/
https://ncbi.nlm.nih.gov/pubmed/19332878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.103036
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