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Precise Gene-Dose Alleles for Chemical Genetics
Modulating gene dose is an effective way to alter protein levels and modify phenotypes to understand gene function. In addition, combining gene-dose alleles with chemical perturbation can provide insight into drug–gene interactions. Here, we present a strategy that combines diverse loss-of-function...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Genetics Society of America
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2691769/ https://ncbi.nlm.nih.gov/pubmed/19332878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.109.103036 |
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