The NBDs that wouldn't die: A cautionary tale of the use of isolated nucleotide binding domains of ABC transporters

COMATOSE (CTS), the plant homologue of Adrenoleukodystrophy protein, is a full length ABC transporter localized in peroxisomes. In a recent article, we reported that the two-nucleotide binding domains of CTS are not functionally equivalent in vivo. Mutations in conserved residues in the Walker A (K4...

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Autori principali: De Marcos Lousa, Carine, Dietrich, Daniela, Johnson, Barbara, Baldwin, Stephen A, Holdsworth, Michael J, Theodoulou, Frederica L, Baker, Alison
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686355/
https://ncbi.nlm.nih.gov/pubmed/19704900
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