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Equal transcription rates of productively and nonproductively rearranged immunoglobulin μ heavy chain alleles in a pro-B cell line

During B cell maturation, immunoglobulin (Ig) genes frequently acquire premature translation-termination codons (PTCs) as a result of the somatic rearrangement of V, D, and J gene segments. However, it is essential for a B lymphocyte to produce only one kind of antibody and therefore to ensure that...

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Detalhes bibliográficos
Main Authors: Eberle, Andrea B., Herrmann, Kai, Jäck, Hans-Martin, Mühlemann, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685528/
https://ncbi.nlm.nih.gov/pubmed/19363217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1516409
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