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Generation and Behavioral Characterization of β-catenin Forebrain-Specific Conditional Knock-Out Mice

The canonical Wnt pathway and β-catenin have been implicated in the pathophysiology of mood disorders. We generated forebrain-specific CRE-mediated conditional β-catenin knockout mice to begin exploring the behavioral implications of decreased Wnt pathway signaling in the central nervous system. In...

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Bibliografiske detaljer
Main Authors: Gould, Todd D., O'Donnell, Kelley C., Picchini, Alyssa M., Dow, Eliot R., Chen, Guang, Manji, Husseini K.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676732/
https://ncbi.nlm.nih.gov/pubmed/18299155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2007.12.028
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