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Methazolamide and Melatonin Inhibit Mitochondrial Cytochrome C Release and Are Neuroprotective in Experimental Models of Ischemic Injury

BACKGROUND AND PURPOSE: The identification of a neuroprotective drug for stroke remains elusive. Given that mitochondria play a key role both in maintaining cellular energetic homeostasis and in triggering the activation of cell death pathways, we evaluated the efficacy of newly identified inhibitor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Xin, Figueroa, Bryan E., Stavrovskaya, Irina G., Zhang, Yi, Sirianni, Ana C., Zhu, Shan, Day, Arthur L., Kristal, Bruce S., Friedlander, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674528/
https://ncbi.nlm.nih.gov/pubmed/19299628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.108.540765
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