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A common signaling cascade may underlie “addiction” to the Src, BCR-ABL, and EGF receptor oncogenes
“Oncogene addiction” describes an unexplained dependency of cancer cells on a particular cellular pathway for survival or proliferation. We report that differential attenuation rates of pro-survival and pro-apoptotic signals in oncogene-dependent cells contribute to cell death following oncogene ina...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673136/ https://ncbi.nlm.nih.gov/pubmed/17097564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2006.09.014 |
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