Fibrinogen-induced endothelin-1 production from endothelial cells

We previously demonstrated that fibrinogen (Fg) binding to the vascular endothelial intercellular adhesion molecule-1 (ICAM-1) leads to microvascular constriction in vivo and in vitro. Although a role of endothelin-1 (ET-1) in this Fg-induced vasoconstriction was suggested, the mechanism of action w...

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Bibliografiske detaljer
Main Authors: Sen, Utpal, Tyagi, Neetu, Patibandla, Phani K., Dean, William L., Tyagi, Suresh C., Roberts, Andrew M., Lominadze, David
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2009
Fag:
Vascular Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670653/
https://ncbi.nlm.nih.gov/pubmed/19193866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00515.2008
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