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Phosphorylation of TRAF2 within its RING domain inhibits stress-induced cell death by promoting IKK and suppressing JNK activation

TRAF2 is an adaptor protein that modulates the activation of the JNK/c-Jun and IKK/NF-κB signaling cascades in response to TNFα stimulation. Although many serine/threonine kinases have been implicated in TNFα-induced IKK activation and NF-κB-dependent gene expression, most of them do not directly ac...

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Bibliografske podrobnosti
Main Authors: Thomas, Gregory S., Zhang, Laiqun, Blackwell, Ken, Habelhah, Hasem
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669835/
https://ncbi.nlm.nih.gov/pubmed/19336568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4867
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