High-Resolution Mapping and Characterization of Open Chromatin across the Genome

Mapping DNase I hypersensitive (HS) sites is an accurate method of identifying the location of genetic regulatory elements, including promoters, enhancers, silencers, insulators, and locus control regions. We employed high-throughput sequencing and whole-genome tiled array strategies to identify DNa...

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Bibliographic Details
Main Authors: Boyle, Alan P., Davis, Sean, Shulha, Hennady P., Meltzer, Paul, Margulies, Elliott H., Weng, Zhiping, Furey, Terrence S., Crawford, Gregory E.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669738/
https://ncbi.nlm.nih.gov/pubmed/18243105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.12.014
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