The Circadian Clock Components CRY1 and CRY2 Are Necessary to Sustain Sex Dimorphism in Mouse Liver Metabolism

In mammals, males and females exhibit anatomical, hormonal, and metabolic differences. A major example of such sex dimorphism in mouse involves hepatic drug metabolism, which is also a noticeable target of circadian timekeeping. However, whether the circadian clock itself contributes to sex-biased m...

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Hlavní autoři: Bur, Isabelle M., Cohen-Solal, Anne M., Carmignac, Danielle, Abecassis, Pierre-Yves, Chauvet, Norbert, Martin, Agnès O., van der Horst, Gijsbertus T. J., Robinson, Iain C. A. F., Maurel, Patrick, Mollard, Patrice, Bonnefont, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Metabolism and Bioenergetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666555/
https://ncbi.nlm.nih.gov/pubmed/19211562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808360200
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