Targeted Killing of Cancer Cells In vivo and In vitro with EGF-directed Carbon Nanotube-based Drug Delivery

Carbon nanotube-based drug delivery holds great promise for cancer therapy. Herein we report the first targeted, in vivo killing of cancer cells using a drug-single wall carbon nanotube (SWNT) bioconjugate, and demonstrate efficacy superior to non-targeted bioconjugates. First line anti-cancer agent...

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Autori principali: Bhirde, Ashwin A., Patel, Vyomesh, Gavard, Julie, Zhang, Guofeng, Sousa, Alioscka A., Masedunskas, Andrius, Leapman, Richard D., Weigert, Roberto, Gutkind, J. Silvio, Rusling, James F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665730/
https://ncbi.nlm.nih.gov/pubmed/19236065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn800551s
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