Early postnatal exposure to methylphenidate alters stress reactivity and increases hippocampal ectopic granule cells in adult rats

To mimic clinical treatment with methylphenidate (MPH; Ritalin) for attention deficit/hyperactivity disorder (ADHD), rat pups were injected with MPH (5 mg/kg, I.P.) or placebo twice daily during their nocturnal active phase from postnatal day (PND) 7 to 35. Thirty-nine days after the last MPH admini...

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Main Authors: Torres-Reveron, Annelyn, Gray, Jason D., Melton, Jay T., Punsoni, Michael, Tabori, Nora E., Ward, Mary J., Frys, Kelly, Iadecola, Costantino, Milner, Teresa A.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663854/
https://ncbi.nlm.nih.gov/pubmed/19100815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2008.11.009
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