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Amiodarone Destabilizes Intracellular Ca(2+) Homeostasis and Biosynthesis of Sterols in Leishmania mexicana

Leishmaniasis represents a serious public health problem worldwide. The first line of treatment is based on glucantime and pentostan, which generate toxic effects in treated patients. We have recently shown that amiodarone, frequently used as an antiarrhythmic, possesses activity against Trypanosoma...

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Detalhes bibliográficos
Main Authors: Serrano-Martín, Xenón, García-Marchan, Yael, Fernandez, Alexis, Rodriguez, Noris, Rojas, Hector, Visbal, Gonzalo, Benaim, Gustavo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663059/
https://ncbi.nlm.nih.gov/pubmed/19164149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01215-08
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