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Role of acylglycerol kinase in LPA-induced IL-8 secretion and transactivation of epidermal growth factor-receptor in human bronchial epithelial cells

LPA (lysophosphatidic acid) is a potent bioactive phospholipid, which regulates a number of diverse cellular responses through G protein-coupled LPA receptors. Intracellular LPA is generated by the phosphorylation of monoacylglycerol by acylglycerol kinase (AGK); however, the role of intracellular L...

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Detalhes bibliográficos
Main Authors: Kalari, Satish, Zhao, Yutong, Spannhake, Ernst Wm., Berdyshev, Evgeny V., Natarajan, Viswanathan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2660210/
https://ncbi.nlm.nih.gov/pubmed/19112101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90431.2008
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